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The region of the heart that initiates the heartbeat is the

  1. Atrioventricular node

  2. Bundle of His

  3. Sinoatrial node

  4. Ventricular node

The correct answer is: Sinoatrial node

The correct answer is C. Sinoatrial node. The Sinoatrial (SA) node, also known as the pacemaker of the heart, is located in the right atrium. It is responsible for initiating the heartbeat by generating electrical impulses. These electrical signals cause the atria to contract, pumping blood into the ventricles. The other options mentioned are involved in the conduction of the electrical impulses through the heart after the initial signal is generated by the SA node.